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Tagln-creert2

WebAug 2, 2024 · TAGLN (transgelin, also known as SM22 or SM22α) is widely accepted as a canonical marker of smooth muscle cells (SMCs) (Li et al., 1996; Lees-Miller et al., 1987; … WebProcr-CreERT2-2A-tdTomato Tmem119-2A-CreERT2 Lgr5-EGFP-IRES-CreERT2 Aqp5-2A-CreERT2. * There are some knockin mice carrying the Dre recombinase gene under the control of the specific promoter. When crossed with a strain containing rox sequences, Dre-mediated recombination results in tissue-specific deletion of flanked sequences in the …

TAGLN Is Downregulated by TRAF6-Mediated Proteasomal …

Web017491 B6.Cg-Tg(Tagln-cre)1Her/J These Tagln-cre (also called Sm22aCre) transgenic mice express Cre recombinase under the control of the mouse smooth muscle protein 22-alpha … WebNov 12, 2014 · Upk3b is dispensable for normal heart formation. Hematoxylin and eosin staining (H&E) and immunofluorescence analysis of markers of capillary endothelia (IB4), cardiomyocytes (MF20), fibroblasts (Postn) and coronary smooth muscle cells (Tagln) on sections of 6-month old hearts of wildtype and homozygous knock-out mice. alexandra quick reddit https://reospecialistgroup.com

Cre-lox系统介绍及使用汇总 - 知乎 - 知乎专栏

WebSep 4, 2024 · Pdgfra-expressing (Pdgfra+) cells have been implicated as progenitors in many mesenchymal tissues.To determine lineage potential, we generated Pdgfra rtTA knockin … WebTg (Tagln-cre/ERT2)1Feil. Mutation details : An allele encoding a tissue-specific and ligand-dependent recombinase was generated by adjoining cre recombinase/modified estrogen … WebThe expressions of TAGLN in colorectal carcinoma tissues, adjacent normal tissues, and LoVo cells were detected by the Western blot method. The recombinant plasmid pcDNA3.1-TAGLN was established and transfected into LoVo cells with the help of Lipofectamine™ 2000. At the same time, the TAGLN siRNA was transfected into LoVo cells in another group. alexandra popp compagnon

Tagln-CreERT2小鼠--兰博模型LABMODEL 兰博动物LABANIMAL 兰 …

Category:工具鼠的工具鼠,Reporter 鼠简介 - 知乎 - 知乎专栏

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Tagln-creert2

An update on the phenotypic switching of vascular smooth

WebMSC-like VSMCs Tagln-CreERT2 Myh11-Cre-ERT2 TCTA2-CreERT2 R26R-lacZ R26R-mT/mG R26R- EYFP Rosa26-tdTomato R26R-Confetti R26R-Brainbow MGP−/− chow diet Apoe−/− … WebTagln tm1(cre/ERT2)Feil: Name: transgelin; targeted mutation 1, Robert Feil: ... Synonyms: SM22alphaCew-ER T2, SM-Cre ER T2 (ki), SM-CreER T2 (ki), SM-CreERT2(ki), Tagln …

Tagln-creert2

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WebResults indicate that TAGLN is a p53 and PTEN-upregulated gene, expressing higher levels in normal bladder epithelial cells than in carcinoma cells. Further, TAGLN inhibited cell proliferation and invasion in vitro and blocked tumorigenesis in vivo. Collectively, it can be concluded that TAGLN is an antitumor gene in the human bladder. WebTagln-CreERT2: Cardiovascular system: Smooth muscle cell: Repository Live * There are some knockin mice carrying the Dre recombinase gene under the control of the specific promoter. When crossed with a strain containing rox sequences, Dre-mediated recombination results in tissue-specific deletion of flanked sequences in the offspring.

WebJul 9, 2024 · Background and Purpose: The role of the cartilage oligomeric matrix protein (COMP) in epithelial-mesenchymal transition (EMT) in tumor progression has been studied, but its exact regulatory mechanism remains unknown.Methods: The interaction between COMP and the actin-binding protein transgelin (TAGLN) was identified by interaction … Web图 2 Tagln Cre/+; Rosa26 tdTomato/+ 小鼠肺部tdTomato的表达情况。 Tagln Cre/+; Rosa26 tdTomato/+ 双转基因鼠,可在小鼠在肺血管平滑肌细胞中检测到tdTomato的表达。 图 3 Tagln Cre/+; Rosa26 tdTomato/+ 小鼠各组织中tdTomato的表达情况。TdTomato的表达在大脑,眼,心,肝,肺,肌肉,胰腺 ...

WebLanguage: English . 中文; 日本語; 한국어; Settings; Exit; Sign in; Products . U-GEMMs . Toolbox of Mice Web将2A-DreERT2插入到小鼠Tagln基因终止密码子处。与此相似的品系还有Tagln-2A-DreERT2(NM-KI-215038)。 应用领域:Dre工具鼠 . 相关品系. Tagln-CreERT2. 品系名: ...

WebAug 2, 2024 · TAGLN (transgelin, also known as SM22 or SM22α) is widely accepted as a canonical marker of smooth muscle cells (SMCs) (Li et al., 1996; Lees-Miller et al., 1987; Amano et al., 1996).In the course of our …

WebApr 4, 2024 · Mutation details: A vector was used to insert IRES-Cre-ER T2 downstream of the stop codon in exon 14. Transient FLP-recombinase excised a FRT-floxed neo 3' to the Cre. ES cell clone XF136.64 was injected into blastocysts to generated mice. alexandra racanelli mdWebNov 9, 2024 · cre 平滑肌 血管 tagln 异性 工具. 血管平滑肌及血管内皮组织特异性cre工具鼠一、血管平滑肌特异性的cre工具鼠:Tagln-creTagln(Transgelin),又称为SM22或SM22a,主要表达于平滑肌细胞中,属于微丝连接蛋白家族。. 是目前血管平滑肌细胞条件性敲除最常用的cre工具鼠 ... alexandra police station addressWebMay 18, 2024 · At 20 dpf, tagln-positive MCs with the typical shape of arterial VSMCs had lost abcc9 expression, which however remained in capillary pericytes ... We also analyzed a newly generated Abcc9-CreERT2;R26-mTmG mice and obtained analogous results to those described for Kcnj8-CreERT2;R26-mTmG mice. alexandra roobottomalexandra rose tozziWebJul 1, 2024 · AbstractTransgelin (TAGLN, also named SM22) is an actin-associated protein and affects dynamics of actin filaments. Deregulation of TAGLN contributes to the development of different cancers, and it is commonly considered to be a tumor suppressor. TAGLN is usually downregulated in prostate cancer; however, the detailed functions of … alexandra scaggs financial timesWeb利用Cre-lox系统在小鼠体内实现对基因的时空特异性打靶(表达或敲除),原则上需要建立两种小鼠。. 首先,建立特异性Cre小鼠,该小鼠中的Cre重组酶由特定启动子驱动,可在特定细胞或组织或全身表达Cre重组酶。. Cre重组的特异性由驱动Cre的启动子或增强子 ... alexandra psihogioshttp://www.labmodel.cn/mod_product-view-p_id-4529.html alexandra sanchez