WebJan 1, 2000 · The ratio of the intracellular concentration to the extracellular concentration (C i /C e) is the parameter used to classify the ability for intraphagocytic accumulation of antibiotics. Poor penetration into the cells and decreased activity intracellularly are the major reasons for the limited activity of most antibiotics (penicillins, cephalosporins, … WebFeb 1, 1990 · DOI: 10.1016/0165-2427(90)90016-L Corpus ID: 22036250; The mechanism of enhanced intraphagocytic killing of bacteria by liposomes containing antibiotics. @article{Dees1990TheMO, title={The mechanism of enhanced intraphagocytic killing of bacteria by liposomes containing antibiotics.}, author={Craig Dees and Ronald D. …
VDR Receptor defect and vitamin D supplementation
WebFeb 1, 1990 · Studies on mechanism of enhanced intraphagocytic killing The mechanism of enhanced intraphagocytic killing of bacteria in bovine phagocytic cells by liposomes … WebThese observations indicate that the inhibition of intraphagocytic bacterial growth by the low intraphagolysosomal p H and other phagolysosomal bacteristatic factors determines the antimicrobial activity of accumulated antibiotics. … thegregster101
Activities of antistaphylococcal antibiotics towards the …
WebNov 2, 2012 · The term intraphagocytic refers to the fact that these bacteria have developed the ability to remain alive and proliferate undetected inside the cytoplasm of the cells they infect. These cells include macrophages, the very cells of the immune system that the body uses to kill invading pathogens. WebThe intraphagocytic activity of erythromycin, roxithromycin and azithromycin against phagocytosedStaphylococcus aureus was compared. Erythromycin and roxithromycin … Webintraphagocytic growth of which was not efficiently controlled by these drugs. In contrast, ceftobiprole showed similar activities against MSSA and MRSA at acid pH in broth and intracellularly. Conclusions: Ceftobiprole shows intraphagocytic activity against MRSA due to its large activity at acid pH. Intraphagocytic Activities of Ceftobiprole ... the gre group