WebMar 22, 2024 · Liver fibrosis is often a consequence of chronic liver injury, and has the potential to progress to cirrhosis and liver cancer. Despite being an important human … WebJun 7, 2016 · Intercross of signaling pathways in liver and lung fibrosis reveals common fibrosis pathway signature. Gene expression data derived from lung dataset GES2052 …
Targeting epigenetically maladapted vascular niche alleviates liver ...
WebFeb 10, 2024 · Metabolic dysfunction-associated fatty liver disease (MAFLD) is a highly heterogeneous disease and its heterogeneity might be associated with ferroptosis because ferroptosis plays an important role in the development of MAFLD. We aimed to perform integrative analysis of ferroptosis related genes and MAFLD subtypes using … WebThe integrated approach of bioinformatics and molecular biology is more efficient to research multi-factorial diseases, such as liver fibrosis and liver cancer. Future studies on the differences on DCN, DPT, and SOX9 expression may help in the better understanding of the mechanisms involved in the development of liver fibrosis and HCC. the singapore grand prix
(PDF) Identification of key genes, pathways and ... - ResearchGate
WebApr 15, 2024 · Objective: To analyze differentially expressed genes (DEGs) related to liver fibrosis, and clarify the key genes and the possible targets in the progression of liver … WebNov 2, 2024 · Liver fibrosis occurs in response to chronic liver injury and is characterized by an excessive deposition of extracellular matrix. Activated hepatic stellate cells are primarily responsible for this process. ... Bioinformatics analysis showed that HLSC-EVs contain several miRNAs that target biological pathways involved in the development of ... Web1 Introduction. Hepatic fibrosis (HF) is an excessive repair response caused by various chronic liver diseases such as viral hepatitis, alcoholic hepatitis, cholestasis, and drug-induced liver injury ().HF is an increasing public health concern worldwide, and may lead to the occurrence of serious high-risk liver diseases such as cirrhosis and liver cancer (2, 3). the singapore resort \u0026 spa